Virtual Poster Session

Welcome to the Virtual Poster Session, a new and powerful tool for networking and information exchange. Here you can share your work, search though the poster library, and start a dialogue with others in your field. Each uploaded poster that pertains to force measurement and testing can currently be used to apply for an academic travel scholarship; please see the Scholarships page for application details and deadlines.

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Submitted by Kevin Valenzuela

Stair negotiation is one of the more difficult daily activities reported by total knee replacement (TKR) patients. Dissatisfied TKR patients have reported increased difficulty with stair negotiation, however it is unknown what the underlying mechanical issues are for this population. Therefore, the purpose of this research was to examine the knee joint biomechanics of dissatisfied TKR patients during stair descent. Nine dissatisfied TKR patients (34.6±14.3 months from surgery), 15 satisfied TKR patients (29.3±12.8 months from surgery), and 15 healthy participants performed stair descent trials on a five-step instrumented staircase at a preferred gait speed. The dissatisfied group showed lower knee extension and abduction moments in their replaced limb. The 2nd peak vertical ground reaction force (VGRF) and 1st and 2nd peak knee internal rotation moments showed lower moments for replaced limbs compared to non-replaced limbs. First peak VGRF was reduced for dissatisfied group compared to satisfied and healthy groups. The dissatisfied TKR group had significantly increased pain levels on their replaced limb compared to all other groups and limbs. The dissatisfied group had reduced gait speed compared to the satisfied and healthy groups. Increased pain levels lead to reduced descent speed and peak loading-response and pushoff sagittal plane knee joint moments in dissatisfied total knee replacement patients during stair descent. This creates an asymmetry in the extension loading response moment for the dissatisfied group, with the non-replaced limb showing increased joint moments whereas the satisfied and healthy groups do not have that imbalance.


Listed In: Biomechanics
Submitted by Lauren Schroeder

Collegiate softball has become increasingly popular since the passage of Title IX. As with any sport, injuries are a common occurrence. Interestingly, the base runner is at the highest risk of injury, and rounding the base, specifically, has resulted in approximately 187 game-day injuries. Rounding the base involves planting the right foot on a raised surface and cutting to the left, a dynamic movement often associated with noncontact ACL injuries. Frontal plane loading and unbalanced quadriceps-to-hamstring co-contraction indices (Q:H CCI) have been associated with increasing the likelihood of noncontact ACL injuries occurring. Neuromuscular abnormalities pre- and post-contact have also been suggested to increase the risk of injury. To date, no study has analyzed the effect of rounding a base on noncontact ACL injury risk factors in softball players. Nine recreationally active females completed two base conditions. The first simulated rounding a base with no base on the force platform (NB), and the second simulated rounding a base with a base on the force platform (WB). Three-dimensional motion capture, one force platform, and electromyography were utilized. Results indicated the WB condition reduced the risk of noncontact ACL injury by decreasing frontal plane loading. Movement patterns at the ankle and abnormal foot strikes may provide a better explanation for why noncontact ACL injuries occur while rounding first base. Post-contact Q:H CCI was significantly greater than pre-contact, indicating significantly greater quadriceps activity post-contact. Neuromuscular training could potentially reduce the load applied to the ACL and decrease the risk of injury.


Submitted by Derek Yocum

Purpose: An increased likelihood of developing obesity-related knee osteoarthritis may be associated with increased peak internal knee abduction moments. Increases in step width may act to reduce this moment. The purpose of this study was to determine the effects of increased step width on knee biomechanics during stair ascent of healthy-weight and obese participants. Methods: Participants ascended stairs while walking at their preferred speed in two different step width conditions – preferred and wide. A 2 x 2 (group x condition) mixed model analysis of variance (ANOVA) was performed to analyze differences between groups and conditions (p<0.05). Results: Increased step width decreased the loading-response peak vertical ground reaction force (GRF), loading-response knee abduction moment, knee extension ROM, and knee abduction ROM in both groups. However, it also increased loading and push-off peak mediolateral GRF, and peak knee abduction angle in both groups. Obese participants experienced a disproportionate increase in loading and push-off peak mediolateral GRF, and peak knee abduction angle compared to healthy. Conclusion: Increased SW successfully decreased loading-response peak knee abduction moment. Implications of this finding are that increased SW may decrease likelihood of developing medial compartment knee osteoarthritis. This study shows that this gait modification affects obese and healthy-weight differently, and the influence of body mass on knee biomechanics.


Listed In: Biomechanics
Submitted by S. Jun Son

Purpose: Knee pain is a chief symptom of knee pathology. Both acute and chronic knee pain result in altered joint loads during walking, which potentially result in mechanical and biological changes in knee articular cartilage. Due to confounding factors in clinical knee pain (effusion, muscle weakness, inflammation, structural changes), it is difficult to examine the independent effect of knee pain on walking mechanics. The purpose of this study is to examine whether unilateral experimentally induced knee pain influences bilateral loading patterns during walking in healthy individuals.
Methods: This study was a controlled laboratory, cross-over trial. Each of 30 able-bodied subjects (M = 20, F = 10; 23 ± 2.4 yrs, 71 ± 12.7 kg, 178 ± 8.2 cm) completed three experimental sessions: pain (5.0% NaCl infusion), sham (0.9% NaCl infusion), and control (no infusion) in a counterbalanced order, 2 days apart (a washout period). For the experimental sessions, hypertonic (5% NaCl) or isotonic (0.9% NaCl) saline was continuously infused into the right (involved limb) infrapatellar fat pad using a portable infusion pump, which produced a continuous saline flow of 0.154mL/min (total 2.16 mL) for 14 min for the pain or sham session, respectively. No infusion was administered to the control session. Subjects and investigators were blinded regarding the saline solution which was being infused. During each of three experimental sessions, subjects performed 30-sec gait trials at a self-selected speed at two time points (pre- and post-infusion). Ground reaction force (GRF) data were collected using an AMTI instrumented force-sensing tandem treadmill (1200 Hz). The first 4 successful gait cycles in each limb were used for data analysis. A functional data analysis approach (α = .05) was used to detect time (pre- and post-infusion) x limb (involved vs. uninvolved) interactions for the vertical, anterior-posterior, and medial-lateral GRF.
Results: Significant time x limb interactions were observed during the pain session (hypertonic saline; 5.0% NaCl; p < .05). Experimental knee pain resulted in up to (i) 0.05 N/kg less vertical GRF and 0.02 N/kg more vertical GRF during various stance phases, (ii) 0.01 N/kg less breaking GRF during loading response, and (iii) 0.007 N/kg less lateral GRF and 0.007 N/kg more lateral GRF during various stance phases in the involved limb.
Conclusions: Relative to the pre-infusion condition, subjects during the knee pain condition tended to walk with less vertical, posterior and lateral GRF in the involved limb (painful limb) across various portions of stance, which simultaneously increased loads in the uninvolved limb (non-painful limb). Our data suggest that compensatory loading patterns occur simultaneously for the involved and uninvolved limbs. This unloading pattern in the involved limb may be due to perception of knee pain, which can make subjects feel fear for damaging or provoking pain more during walking. Moreover, voluntary and/or involuntary quadriceps inhibition (e.g., neuromuscular activation and strength) due to experimentally induced knee pain may play a role in reducing the loads in the involved limb because the quadriceps support the center of body mass eccentrically from initial loading response to midstance to prevent collapse of the lower limbs. These asymmetrical loading patterns due to knee pain and associated with neural inhibition may be a risk factor for knee joint disease progression via changes in mechanical components.


Listed In: Biomechanics, Gait
Submitted by Matthias König

This study examined triceps surae muscle strength and tendon stiffness in young adult elite sprinters and jumpers over one season, in order to detect potential discordance between muscle and tendon adaptation due to training. Furthermore, we examined the effect of habitual training on triceps surae muscle-tendon unit (MTU) mechanical properties in young and older athletes, using a cross-sectional design.
Eleven healthy younger elite sprinters and jumpers, 12 master athletes, 12 recreationally active young controls and one young elite athlete, 10 months after unilateral Achilles tendon reconstruction participated. All young athletes underwent regular measurements over one season. Triceps surae muscle strength and tendon stiffness of both legs were analysed using dynamometry and ultrasonography synchronously.
Within one season, similar patterns of relative changes in muscle strength and tendon stiffness were seen in the young elite athletes. For the tendon reconstruction athlete, the affected leg showed no increases in muscle strength or tendon stiffness over one season, and remarkably lower muscle strength but similar tendon stiffness compared to the non-affected leg. Healthy young elite athletes showed higher muscle strength and tendon stiffness than both other subject groups, with no differences between young controls and master athletes.
Our results provide evidence for training-induced concordant adaptation of muscle and tendon over one season within healthy young elite athletes. Achilles tendon rupture and reconstruction may be a major risk factor for irreversible discordance within the triceps surae MTU. Finally, habitual athletics training over the lifespan may effectively counteract age-related decreases in muscle strength and tendon stiffness.


Submitted by Matthew Titchenal

Purpose:
Anterior cruciate ligament (ACL) tear greatly increases the risk of knee osteoarthritis (OA), even when patients undergo ACL reconstruction surgery (ACLR). Changes to walking kinematics following ACLR have been suggested to play a role in this degenerative path to post-traumatic OA by shifting the location of repetitive joint contact loads that occur during walking to regions of cartilage not conditioned for altered loads. Recent work has shown that changes to the average knee center of rotation during walking (KCOR) between 2 and 4 years after ACLR are associated with long term changes in patient reported outcomes at 8 years. Changes to KCOR result in changes to contact patterns between the femur and the tibial plateau. However, it is unknown if changes to this kinematic measure are reflected by changes to cartilage as early as 2 years after surgery. Ultrashort TE-enhanced T2* (UTE-T2*) mapping has been shown to be sensitive to subsurface changes occurring in deep articular cartilage early after ACL injury and over 2 years after ACLR that were not detectable by standard morphological MRI. Thus, the purpose of this study was to test the hypothesis that side to side differences in KCOR correlate with side to side differences in UTE-T2* quantitative MRI (qMRI) in the central weight bearing regions of the medial and lateral tibial plateaus at 2 years following ACLR.

Methods:
Thirty-five human participants (18F, Age: 33.8±10.5 yrs, BMI: 24.1±3.3) with a history of unilateral ACL reconstruction (2.19±0.22 yrs post-surgery) and no other history of serious lower limb injury received bilateral examinations on a 3T MRI scanner. UTE-T2* maps were calculated via mono-exponential fitting on a series of T2*-weighted MR images acquired at eight TEs (32μs -16 ms, non-uniform echo spacing) using a radial out 3D cones acquisition. All subjects completed bilateral gait analysis. Medial-lateral (ML) and anterior-posterior (AP) coordinates of average KCOR during stance of walking were calculated for both knees. Side to side differences in KCOR were tested for correlations with side to side differences in mean full thickness UTE-T2* quantitative values in the central weight bearing regions of the medial and lateral tibial plateau using Pearson correlation coefficients.

Results:
There was a distribution in UTE-T2* values, with some subjects having higher UTE-T2* and some lower in the ACLR knee relative to the contralateral knee. A significant correlation (R=0.407, p=0.015, Figure 1A) was observed between UTE-T2* and the ML KCOR with a more lateral KCOR corresponding to higher values of UTE-T2* for the medial tibia. Similarly, for the lateral tibia, a lower UTE-T2* was correlated with a more posterior KCOR (R=0.363, p=0.032, Figure 1B). Significant correlations were not observed for UTE-T2* in the lateral tibia with the ML position of KCOR or for UTE-T2* in the medial tibia with the AP position of KCOR.

Conclusions:
The results of this study support the hypothesis that side to side differences in mean full thickness UTE-T2* qMRI correlate with side to side differences in knee kinematics at 2 years after ACLR. The finding that a more lateral KCOR in the ACLR knee correlates with UTE T2* values in the medial tibia that were higher than the contralateral side suggests that this kinematic change, which has been previously shown to result in more relative motion between the femur and tibia in the medial compartment, could be affecting subsurface matrix integrity, inducing changes detectable by UTE-T2* mapping. Additionally, the finding that a more posterior KCOR in the ACLR knee correlated with UTE-T2* values in the lateral tibia that were lower than the contralateral knee further suggests that the UTE-T2* metric may reflect early changes in cartilage health. When interpreted within the context of prior work showing that a posterior shift in KCOR from 2 to 4 years post-surgery correlated with improved clinical outcomes at 8 years, the observed lower UTE-T2* with a more posterior KCOR, which is reflective of improved quadriceps recruitment, suggests positive cartilage matrix properties. In spite of the limitations of this cross-sectional and exploratory study, and the difficulty accounting for changes in the contralateral knee, these results support future studies of the relationship between UTE-T2* and KCOR to provide new insight into predicting the risk for OA after ACLR.


Submitted by Patrick Carden

Analysis of lower limb biomechanics during jumping and landing tasks are often used to assess lower limb injury risk in research and applied practice within professional team sports. However, there are limited instances of these movements being incorporated into research focusing on Achilles tendinopathy development. PURPOSE: To investigate whether differences existed in lower limb motion and moments during jumping and landing between individuals who develop Achilles tendinopathy and those who remain injury free. METHODS: Male professional Rugby Union players without lower limb injury (n = 43) were compared to players who sustained Achilles tendinopathy (n = 8). Five single-leg drop vertical jumps per leg were performed at the start of their pre-season training. Motion of the lower limbs were recorded synchronously with ground reaction force. RESULTS: Players who sustained Achilles tendinopathy demonstrated significantly increased rear-foot inversion-eversion range of motion (p = 0.03), a reduction in dorsi-plantarflexion range of motion (p = 0.01) and knee flexion-extension range of motion (p = 0.03). Peak dorsiflexion velocity (p = 0.02) and peak knee flexion velocity were also reduced in those with Achilles tendinopathy (p = 0.03). No differences in hip joint kinematics were observed. Controls displayed slightly larger peak plantarflexion moments; however this difference was not statistically significant (p = 0.15, g = 0.60). CONCLUSIONS: The findings indicated that players who subsequently developed Achilles tendinopathy displayed an altered single leg landing strategy when compared to players who did not sustain injury; with motion of the ankle joint and rear-foot most influenced.


Submitted by Jocelyn Hafer

INTRODUCTION. Increased age is associated with changes in gait mechanics and decreased muscle function. As the knee extensors (KE) are prime movers in gait, altered KE function (strength, power, fatigability) could alter knee mechanics. This study aimed to determine whether a bout of exercise induces KE fatigue and changes in knee mechanics in two older groups with different physical activity levels: sedentary adults and runners.

METHODS. Adults aged 55-70 who were either runners (≥15 miles/wk) or sedentary (≤3x30 min exercise bouts/wk) completed gait and strength testing before and after a 30 minute treadmill walk (30MTW). Joint kinematics were calculated using the point cluster technique. Externally-referenced moments were calculated using inverse dynamics. KE power and isometric strength were assessed via isokinetic dynamometry. Changes in KE power and knee mechanics were calculated; within-group changes were examined using paired t-tests (p<0.1).

RESULTS. Sedentary adults displayed a drop in KE power at 6/8 contraction velocities vs. 2/8 in runners (poster Figure 2). Both groups showed an increase in knee flexion angle at heel strike and runners displayed decreased knee flexion moments post-30MTW (poster Figure 3).

CONCLUSIONS. Vigorous physical activity may allow older adults to maintain fatigue resistance. Sensitivity of knee mechanics to KE fatigue remains unclear as few changes were seen even in a fatigued group. Global, rather than discrete, measures of joint function may provide more sensitive measures of the response of gait mechanics to muscle fatigue and may allow for a more complete picture of the impact of muscle function on gait.


Listed In: Biomechanics, Gait
Submitted by Melissa Mansfield

Physical testing of TKR systems to assess stability is an important aspect in screening candidate TKR designs which can be expensive and time consuming. Costs can be reduced by utilizing 3D printed plastic components. The objective is to compare the kinematics and intrinsic constraint of metal-on-plastic (M-P) and plastic-on-plastic (P-P) implants under physiologically relevant loading, with and without simulated ligament contributions, in order to elucidate the effects of material pairings. A cruciate retaining TKR implant was created by combining a 3D printed ABS plastic tibial component with the standard cobalt chrome femoral component, as well as a 3D printed ABS plastic replica femoral component. This results in both M-P and P-P articulations that were mounted to a VIVO 6-DOF joint motion simulator (AMTI, Watertown, MA), which was used for in vitro constraint testing using functional laxity tests. Anterior-posterior (AP) and internal-external (IE) constraint was measured based on resulting deviations from the normal path when superimposed AP and IE loads were applied. Ligaments were simulated as tension-only point-to-point springs using the soft tissue modelling capabilities of the VIVO. Different kinematics were observed between the M-P and P-P implants which could be the result of different initial implant positioning on the joint motion simulator or due to “stiction” of the P-P implant. The functional laxity of the implant system tested appears to be relatively insensitive to the material pairing and ligament presence. These relationships are complex and hard to predict, which underscores the importance of pre-clinical in vitro testing.


Submitted by Rakshatha Kabbaligere

Multisensory integration is driven by a process of sensory reweighting during which each input is assigned a weight depending on the current functional state of a particular sensory system, the task itself and the context in which it is being performed. The primary aim of this study was to determine which of the two inputs between ankle proprioception and vision is upweighed during a postural control task when the two inputs provide conflicting information pertaining to direction of body sway. Achilles tendon vibration and visual flow were used to create sensory conflict, which produced center of pressure (COP) sway in opposite directions when applied independently. The baseline conditions (1) consisted of eyes open quiet stance condition, eyes closed with vibration applied on the Achilles tendons (2) and eyes open with visual flow (3). The experimental condition simultaneously combined vibration and visual flow. COP excursions were recorded in 10 healthy young adults to evaluate the magnitude and direction of sway produced by vibration and/or visual flow. Additionally, lower body joint kinematics were evaluated to understand the multi-segmental strategies and their adaptation to the various sensory manipulations. The results showed that visual flow moderated the extent of backward COP and ankle angular displacement produced when vibration was applied independently. Additionally, visual flow was also found to reduce the extent of predominant hip strategy generated by ankle vibration. The findings show that visual input plays a significant role in maintaining stability and that ankle proprioception is downweighed during conflicts between vision and proprioception. This has important implication for balance training using controlled visual flow in patients with balance disorders and elderly.