Peripheral arterial disease

Positive Ankle Work is Decreased in Peripheral Arterial Disease Before the Onset of Claudication Pain

Peripheral arterial disease (PAD) is a vascular disease characterized by atherosclerotic blockages restricting blood flow to the lower extremities causing pain and discomfort with physical activity. Several studies have previously found decrements in ambulation associated with PAD, such as decreased joint moments and powers before and after the onset of claudication pain [1]. With decreases in moments and powers, the joint work may also be decremented as well. Thus, the purpose of this study was to investigate the positive and negative work at the ankle, knee and hip of PAD patients in a pain-free condition and compare them to gait-velocity matched controls. Five patients with PAD and five healthy older controls were consented for participation. Subjects walked along a 10-meter walkway at their own self-selected speed while kinematics and kinetics were recorded. Each subject rested one minute between trials to mitigate fatigue and prevent ischemic pain. The positive and negative joint work for the PAD patients’ affected limb and the right limb of each control were analyzed and compared through independent t-tests (α=0.05). Five PAD patients (66.6 + 6.2 years; 178.2 + 9.3 cm; 102.6 + 18.5 kg; 1.16 + 0.07 m/s) and five controls (69 + 4.6 years; 174.5 + 1.6 cm; 79.4 + 8.14 kg; 1.30 + 0.09 m/s) were used for analysis. From this study it was found that patients with PAD exhibit a 26% reduction in positive ankle joint work during stance phase than their healthy counterparts (p=0.012).
Listed In: Biomechanics